Purpose and objectives
The aim of the programme Human measurement models is to facilitate the development of new, more efficient human measurement models for health research to ensure that research results can be applied better and faster in humans. The focus of the programme’s second call is to develop innovative human measurement models for disease research or the prevention of diseases, including toxicity studies. The results from health research and any developed model has to be applicable for multiple diseases, and has to have an impact for multiple patient groups.
Budget and lead time
The call for proposals has opened in March 2020 for applications that contribute to the aim of the programme. Depending on the type of research (fundamental, industrial or experimental) and the contributions from private and public parties within the collaborative project, funding between 0.5 and 1 million euros can be requested per research project. The deadline for application is, after extension due to corona, 3 November 2020 at 14.00 hours.
Every day, millions of people have to deal with the consequences of serious and sometimes life-threatening diseases. NWO Domain AES, the SGF, ZonMw and Top Sector LSH are committed to contribute to better and longer healthier lives for everyone. Scientific research, to develop better treatments for example, is crucial. Research models based on human material such as cells and tissues, or computer models based on human data, are expected to resemble humans better than animal models. The more closely a research model resembles the human situation, the sooner the corresponding research results can be applied in practice.
In this context, SGF, NWO Domain AES, ZonMw and Top Sector LSH set up the programme Human measurement models. In 2019, the first funding round of the programme took place, entitled “Human measurement models. Towards better human measurement models”. The current (second) call “Human measurement models 2.0: for health research on diseases and prevention” opened in March 2020, and is coordinated by NWO Domain AES.
(in order of project number)
- Proof-of-concept for a human heart model to test patient-specific therapy-responsiveness (PROPER-THERAPY) - J. van der Velden, PhD, Amsterdam UMC, location VUmc (18953)
- Interoceptive Processing Associated with Bladder Control: Mind the Gap (IP-ABC study) - prof. dr. G.A. van Koeveringe, Maastricht University (18954)
- Non-invasive continuous gut microbial fermentation measurement for health and disease - prof. dr. E. Blaak, Maastricht University (18956)
- CONNECT: Connecting the Blood-Brain Barrier to Cerebral Organoids - prof. dr. E.M. Hol, University Medical Center Utrecht (UMCU) (18957)
- Retina-on-chip: Modeling and Treating Eye Diseases in a Dish (RoC-ME) - A. Garanto, PhD, Radboudumc (18958)
- Virtual Cerebrovascular Responses: modeling the human cortical vasculature to understand brain function in health and disease - dr. N. Petridou, University Medical Center Utrecht (UMCU) (18969)