Idea Generator (NWA-IDG)

(Young) researchers from the entire knowledge chain can apply for funding for high-risk and small-scale projects with a potential for social impact.

  • Aim and objectives

    The Idea Generator call wants to promote research with a potentially high social impact that is risky or too early in its development for an assessment in a regular peer review process. The program encourages creative, out-of-the-box thinkers to put into practice creative, exciting and innovative research ideas that are relevant to the NWA program. Within the Idea Generator, small projects can be funded to further develop an innovative idea by doing research. Applicants from all disciplines, with a practical, applied or fundamental focus, are welcome. (Young) researchers can submit an application individually, but can also do this with fellow applicants.

  • Budget and duration

    The total budget for this programme was 2 million euros.

  • Awarded projects 2019-1

    Disease biomarker detection for Ebola and Lassa virus induced vasculopathy
    Y. Abouleila (Universiteit Leiden)

    A novel platform that combines organ-on-a-chip and mass spectrometry will be used to investigate novel metabolic biomarkers for the early detection of Ebola and Lassa diseases as well as the development of suitable effective treatments.

    Case: Broeikasgassen voor chemische industrie? [Only available in Dutch]

    Challenging the dogma of tick-borne disease transmission: can the expansion of a rodent species trigger the outbreak of tick-borne encephalitis virus?
    J.W. Bakker (Wageningen University & Research)

    The recent spread of tick-borne encephalitis virus in the Netherlands was unexpected. Our experimental project aims to understand whether an expanding mouse species is the driving factor behind the emergence of this tick-borne disease in the Netherlands. This will allow us to understand the transmission pathways of the virus.

    Integration of machine learning and mechanistic models to analyse network dynamics
    Dr. J.B. Beltman (Universiteit Leiden)

    Mathematical models that describe dynamic changes of biological networks based on known and as on yet unknown mechanisms are good at predicting network behaviour, but are time-consuming to develop. In this project, the researchers generate such mechanistic models based on machine learning, speeding up model development.

    How do people who voluntary stop eating and drinking (VSED) die? A prospective study among people who chose for VSED, their relatives and care professionals
    E.E. Bolt (Amsterdam MC)

    Older people who want a self-directed death can voluntary stop eating and drinking. This method has been discussed for over 20 years, but little is known about, for instance, whether it leads to unnecessary suffering. This study gives insight in whether and how this method can be used in practice.

    Is air pollution behind dementia? Unraveling the origin of magnetite nanoparticles in the brain
    Dr. L. Bossoni (Leiden University Medical Center)

    Iron-nanoparticles in the brain have been proposed as a risk factor for dementia. The origin of this mineralized iron is unknown, however air-pollution has been blamed as a possible culprit. Magnetic and structural analyses will help to unravel the origin of these particles and their role in neurodegeneration.

    An antibiotic-free treatment of drug-resistant tuberculosis
    Dr. J. Buter (Rijks Universiteit Groningen)

    Tuberculosis kills 1.3-1.5 million people annually. With the emerging drug-resistance it poses a major global health treat. By tricking the bacterium into metabolic uptake of a photosensitizer a new ground- breaking therapy will be developed. By irradiation with light, the surface-attached photosensitizer will produce reactive oxygen species that kill the bacterium.

    Plasticity Determination of Plants' Root System by Animal Neurotransmitters Assessed with Magnetic Resonance Spectroscopy
    Dr. Y. Caspi (Universiteit Utrecht)

    Animal neurotransmitters, found also in plants, help to shape the plant root system by interacting with their main growth hormones. More insight the interaction between neurotransmitters and hormones will help to develop a rudimentary understanding of plasticity principles that operate in multicellular organisms. In this study the researchers will use magnetic resonance spectroscopy.

    Identification of new leads active against Gram-positive and negative pathogens: the potential of resveratrol derivatives
    Dr. R. Cebrian Castillo (Rijks Universiteit Groningen)

    Antimicrobial resistance (AMR) is an increasingly severe threat to global public health that requires the action of governments and society. The identification of new, safe, and potent drugs active against new targets, especially in Gram-negative bacteria is critical. Resveratrol derivatives offer an excellent scaffold fulfilling the drug requirement.

    Case: Red wine contains source of alternative antibiotic

    What’s app: Testing a new assessment procedure to inform treatment for detained juvenile offenders
    Dr. H.E. Creemers (University of Amsterdam)

    This project aims to examine the applicability and validity of a digital, engaging application to assess risks, needs and learning abilities of short staying offenders in Juvenile Detention Centers. This information, which is in current practice often unavailable, is needed to direct these juveniles to tailored treatment to prevent re-offending.

    Is a dialect speaking robot more easily accepted by the elderly?
    J. van Doorn (Rijks Universiteit Groningen)

    Although the accessibility of technological applications to support elderly people in their daily lives should have increased by speech technology, elderly are still reluctant to use them. This multi- disciplinary project investigates whether the experience elderly have with technology improves if the speech technology uses their native regional language.

    Lucid dreaming as a model for EEG-based communication in locked-in syndrome
    Dr. M. Dresler (Radboud Universitair Medisch Centrum)

    It remains a problem to determine whether paralysed people are still conscious. To find out, a patient can learn to control a computer using their brain signals. This study focusses on the question whether lucid dreamers are able to control such a BCI. In that case, future studies can utilise this more accessible group.

    A gamified application for citizens' participation in urban green space design
    E.D. Ekkel (Aeres Groep)

    An attractive green space contributes to healthy people. This project aims to develop an application that allows residents to access a game in which they are able to create their own public green space. This gives them the opportunity to actively contribute to a green and healthy neighbourhood.

    An artscience approach to Kombucha and plant based living fabrics for sustainable fashion, hydroponics and circular economy
    Dr. R.N. Frese (Vrije Universiteit Amsterdam)

    Artists and scientists join forces to create a biomaterial from water, algae, bacteria, yeast and plants that contains the resources for the four most basic human needs: food, drink, energy and clothing. Maybe we people will be wearing their living, breathing and photosynthesizing clothes soon.

    Case: Circular clothing from kombucha

    Does environmental pollution enhance the allergenic nature of pollen?
    Dr. W.D. Gosling (Universiteit van Amsterdam)

    It is estimated that about 3 million Dutch people suffer from hay fever after contact with airborne pollen. Air pollution in cities possibly makes pollen more allergenic. This project will investigate whether the different types of pollen in cities are chemically changed and whether these changes differ during the year.

    Self-organising adaptation: a universal mechanism for microbial protein expression regulation
    D.H. de Groot (Vrije Universiteit)

    Cells can adapt to, and grow in, an astounding number of environments. Given the simplicity of an individual cell this feat seems impossible. But what if many cells join their forces? The researches propose a universal mechanism that enables a population to survive, but where each individual cell would fail.

    Case: Broeikasgassen voor chemische industrie? [Only available in Dutch]

    Recovering memories ‘thought-to-be-lost’ in the sleep-deprived brain
    Dr. R. Havekes (Rijks Universiteit Groningen)

    Sleep loss is detrimental for the brain and causes memory impairments. It is unclear, however, whether sleep deprivation affects information storage or the retrievability of stored memories. The project examines whether memories ‘thought-to-be-lost’ can be retrieved from the sleep-deprived brain. For this state-of-the-art approaches to modulate brain activity and behavioural studies will be used.

    Demand response voor open water systemen en kunstwerken
    Ir. T.J.T. van der Heijden (TUD)

    The intermittency of renewable energy sources has a destabilizing effect on the grid, together with random changes in electricity use. The Dutch water system contains 221MW of pump-power, which could be used for grid-stabilizing purposes. Research on optimally using the available storage in the water system could accelerate the Dutch energy transition.

    Case: Circular clothing from kombucha

    Restored sound localization for hearing impaired people
    Dr. Ir. R.C. Hendriks (Technische Universiteit Delft)

    The inability of hearing impaired people to localize sound has a big impact on their well-being and self- reliance. Compared to normal-hearing people, hearing-impaired people cannot efficiently use the same localization information. In this project will be investigated whether inaudible localization information can be transformed into a different audible form.

    Off-the-shelf umbilical cord blood derived natural killer cells for cancer immunotherapy
    P.K.J.D. de Jonge (Radboud Universitair Medisch Centrum)

    Natural killer cell therapy is an interesting relatively new immunotherapy-showing efficacy with little side effects. Currently, the personalized nature and long culture times result in high cost and difficult logistics. This project aims to generate a cryopreserved, off-the-shelve product, allowing immediate application at greatly reduced cost.

    Hoe ontstaat de kansenkloof? Lessen uit Nederlandse big data over de gezondheid en ontwikkeling van kinderen.
    C.W.A. van de Kraats (Vrije Universiteit)

    Children growing up in low-income households have, on average, lower earnings in adulthood and lead unhealthier lives. To what extent are these unequal outcomes driven by unequal opportunities? This project uses novel data on childhood development in the Netherlands to study the origins of the childhood opportunity gap.

    Disturbance of the axon-myelin synapse as root cause for multiple sclerosis
    A. Luchicchi (Amsterdam UMC)

    Multiple sclerosis might not be a primary autoimmune disease, as hitherto believed. Instead, this devastating disease may start in the central nervous system and trigger the immune system only secondarily. By employing high-end cellular neuroimaging, the project will demonstrate the correct causal chain of events, from a wholly different starting point.

    Vivianite for lake restoration and phosphate recovery
    Dr. M.F.L.L.W. Lurling (Wageningen University & Research)

    The accumulation of phosphate in lakebeds is one of the most important causes of poor surface water quality. The idea is to develop a novel technique stimulating the formation of a stable iron-phosphate mineral, vivianite, that can be harvested magnetically. This method will promote reuse of phosphorus.

    The Unconscious Road to Alleviating Body Image Concerns: A Novel Evaluative Conditioning Approach using Continuous Flash Suppression
    I. Masselman (Rijks Universiteit Groningen)

    Negative body image (NBI) is a frequent problem with potentially serious consequences. To tackle NBI, researchers test the efficacy of a novel unconscious conditioning procedure in which own-body pictures are paired with positive feedback. Unconscious conditioning may outperform existing interventions because it prevents the disadvantageous (re)activation of negative body-associations.

    Family matters in the prediction of juvenile delinquency: Sustainable solutions for the Kingdom of the Netherlands
    M. Meijeren (Fontys Hogeschool)

    This project questions the usefulness of dominant western models of risk-taxation and crime control in non-western environments. It investigates what risk and protective family factors may fuel or prevent delinquent behaviour in Caribbean youth in Curacao and the Netherlands and how they give insight in the understanding of the criminal paths (not) taken in these specific cultural contexts.

    Do ethnic and gender stereotypes lead to disparities in child protection decision-making?
    F. Middel (Rijks Universiteit Groningen)

    In cases of suspected child maltreatment, parent ethnicity and gender seem to affect child protection decision-making. This study will investigate how ethnic and gender stereotypes influence investigations after children have been reported to child protection agencies and subsequent decision- making in the Netherlands and the United States.

    The new scholastic landscape: Ambient technology to support people with autism
    Prof. dr. ir. M. Mohammadi (Hogeschool van Arnhem en Nijmegen)

    The current physical space of a school is static and therefore not suitable for appropriate education. Integration of ambient technology makes it possible to create a sensitive and dynamic environment. In this project it is investigated how a school with ambient technology can offer added value for children with autism.

    Case: Red wine contains source of alternative antibiotic

    Reliable and rapid evaluation of clinical evidence in the public domain
    Prof. dr. W.M. Otte (Universiteit Utrecht)

    Reliable interpretation of clinical data is hampered by required and time-consuming replication studies. The researchers want to develop a generic calibration model based on 200,000 previously published clinical trials. This model will allow proper and instantaneous interpretation of new data. A user-friendly interface will provide access to everyone.

    Switch from urgency- to benefit-based organ allocation
    Prof. dr. H. Putter (Universiteit Leiden)

    Donor organs are scarce. It is not possible to transplant all patients. Currently, the sickest patients are prioritized to receive organs over others who are less sick. However, less sick patients will live longer after transplantation. This study investigates how to distribute organs so that everyone benefits the most.

    Exploring the impact of dating apps on the heterogeneity of Dutch couples
    G. Ranzini (Vrije Universiteit)

    The popularization of online dating has been linked to the increase in interracial marriages in many Western countries. This project aims to explore the effects of online dating on the broader heterogeneity of Dutch couples through a survey, and based on a lab experiment.

    Case: Red wine contains source of alternative antibiotic

    Experimental evolution of beneficial soil microbiomes
    Dr. D.E. Rozen (Universiteit Leiden)

    Plant diseases reduce crop yields and threaten food security for the growing population. This project helps to develop a novel and environmentally friendly solution to this problem, by evolving microbial communities that suppress infection caused by soil-borne plant pathogens. When effective it will reduce the use of pesticides and fertilizers and enhance food security.

    Bullying and Aggression in Nursing Homes: Types, Motivations, Prevalence, and Consequences
    Dr. J.J. Sijtsema (Tilburg University)

    Bullying and interpersonal aggression in older adults can have a severe impact on their quality of life, but is currently understudied. By applying insights and methods from child and adolescent literature, the role of social relationships and social dynamics on bullying and aggression in residents of nursing homes is examined.

    Converting the greenhouse gases methane and carbon dioxide into value-added products
    Dr. J.C. Slootweg (Universiteit van Amsterdam)

    This project aims at developing a direct transformation of methane via C–H activation and subsequent bond formation with carbon dioxide into the platform chemical acetic acid. This radically new, atom efficient methodology will contribute to optimize resource efficiency across chemical value chains and promote a closed-loop, waste-free society.

    Case: Broeikasgassen voor chemische industrie? [Only available in Dutch]

    Ultimate remedium or optimum remedium? Towards resilient forms of restorative dispute resolution in local community safety
    Dr. R. van Steden (VU)

    This research seeks to experiment with restorative ways of working and dispute resolution in crime reporting processes in the Dutch police. The aim is to develop a new type of police professional, who is able to transcend boundaries between criminal justice and restorative justice, and operates in a networked mode.

    Reframing PJU, a contribution to current discussions on the decolonisation of museum collections and the development of experimental qualitative research methods
    A.G.E. Stultiens (Koninklijke Academie voor de Kunsten)

    New information and contexts are added to photographs and films made on the African continent by explorer Paul Julien, which is part of that is part of the collection of the Nederlands Fotomuseum in Rotterdam. This is done through collaborations with people who have a direct connection with what is shown on the footage.

    Case: Circular clothing from kombucha

    Straight Walking Again: Continuous Sensory Rehabilitation through Real-Time Feedforward
    Drs. T.A.M. Theunissen (Hogeschool van Arnhem en Nijmegen)

    For CVA-patients continuous training is essential to retain lost functionality. The excellent facilities and training from the clinic should be extended to the activities of daily life. We propose a solution that patients can use effectively in the clinic and after that at home and work by using sensory feedforward.

    How to put a break on rumination: tracking effects of fantasizing- and mindfulness-based interventions on depressive vulnerability in the wild.
    Dr. M.J. van Tol (RUG)

    Persistent negative thinking is a key characteristics of recurrent Major Depressive Disorder. Therapeutic techniques, including fantasizing and mindfulness, seem potent in reducing negative thoughts but may rely on different mechanisms. The project will develop ways to objectively track negative thinking and study how changing this can prevent recurrent depression.

    Ex-vivo dialysis of human kidneys for regenerative medicine
    F.M.R. Witjas (Universiteit Leiden)

    The idea is to develop a dialysis-driven organ culture system in which a human kidney can kept alive outside the human body for a prolonged period of time (up to 7-14 days). Consequently, it is tested if new regenerative therapies, such as stem cells, are effective in human organs.

  • Awarded projects 2019-2

    Dike Monitoring for Crack Detection with Distributed Temperature Sensing based Convolutional Neural Network
    J.P. Aguilar-Lopez (Delft University of Technology)

    Cracks occurring on dike surface due to droughts is a big threat for the safety of flood defence infrastructure. A novel dike monitoring technology is proposed, combining the cost effective and accurate distributed temperature sensing (DTS) measurements with innovative image classification and object detection method (Neural Networks).

    Using AI for consumer protection – creating AI based persona for mystery shopping
    Dr. C.A.N.M.Y. Cauffman (Maastricht University)

    This project concerns a feasibility study for an AI based tool that automatically generates personas and ‘mystery shops’ online. This tool can help consumer authorities to efficiently detect consumer law infringements and academics to collect information on online sellers’ use of big data to personalise prices and shopping experiences.

    Improving the accessibility of textual historical collections via transfer learning
    G. Colavizza (University of Amsterdam)

    Digitized heritage collections are becoming abundant thanks to years of efforts from heritage institutions all over the world. We can now work on making these collections better accessible by the public. We will apply novel transfer learning techniques to help make searching heritage collections as smooth as searching the Web.

    Micro-architecture property-space and optimum functional conditions mapping of bioinspired multi-material 3D printable composites with the use of finite element method in conjunction with machine learning algorithms
    M. Cruz Saldivar (Delft University of Technology)

    Several design principles (e.g., hierarchy, functional gradient) exist in natural materials. The synergy between several design principles is responsible for their optimum properties. Our aim to mimic the natural design paradigms and create a platform using machine learning approach to design advanced materials with target properties.

    The local network evaluation field kit
    S.C. Douglas (Utrecht University)

    Two million Dutch adults lack the literacy, numeracy, and digital skills to fully participate in society. Local networks of public, private, and community organizations that collaborate to address this problem lack the tools to evaluate their joint efforts. This project develops a field kit to help networks learn what works.

    Single-molecule analysis of chaperone-assisted folding of androgen receptor for innovative drug discovery
    T.M.J. Evers (Leiden University)

    Androgens are critically involved in disease processes including infertility and cancer. Thus, the androgen receptor protein is a desired drug target. A prerequisite for drug development is to know the structure of this protein. This is a major challenge as the protein is highly dynamic and aggregates.

    Resuscitation decisions in Dutch hospitals: perspectives of patients, relatives and health care professionals
    E.C.T. (Eric) Geijteman (Erasmus MC)
    Consortiumpartner: Patiëntenfederatie Nederland

    For decades, there has been a debate about when and how resuscitation decisions in hospitals should be made. This study will gain insight into experiences and perspectives of patients, their relatives and health care professionals on the questions when and how resuscitation decisions in hospitals must take place.

    Quantum Algorithm Recursion
    Dr. ir. M.E.T. Gerards (University of Twente)

    Quantum algorithms are considered difficult to understand. The researcher working on this project develops a methodology that makes it easier to understand quantum algorithms. Based on this methodology, a proof-of- concept quantum programming language is designed that provides insights into the working of these algorithms.

    Treating virus infections in mosquitoes – a novel strategy to prevent disease transmission
    R. Halbach (Radboud University Medical Center)

    Aedes mosquitoes transmit human viruses including dengue and Zika. Insecticide treatment is the standard strategy to prevent virus transmission; yet it rapidly induces insecticide-resistant mosquitoes and causes collateral damage to pollinating insects. Here, the researchers aim to develop a novel, environmentally friendly approach to prevent virus transmission

    Juveniles’ influence on probation officers’ practice
    Prof dr. A.T. Harder (Erasmus University Rotterdam)

    What can probation officers learn from ex-offenders when it concerns empathy and communication skills? In this study, using storytelling, observations, audio-reflections and survey data, we look at what experience experts convey to professionals, how professionals experience this transfer, and what they use in their daily practice as probation officers.

    Redesigning dosing schedules to reverse antibiotic resistance
    Dr. J.G.C. van Hasselt PhD (Leiden University)

    Chronic bacterial infections in patients with cystic fibrosis (CF) are poorly treatable with antibiotic therapy. Over time, resistance against multiple antibiotics often develops. We will develop a novel combination dosing strategy to prevent or reverse emergence of antibiotic resistance in CF patients, combining advanced laboratory models and mathematical modelling.

    Using simulation modelling to improve food safety: the case of Campylobacter contamination in poultry (CAMPYNAMICS)
    A. Horvat PhD (Wageningen University & Research)

    Campylobacteriosis is the most frequently reported foodborne disease and is not under control. Current biosecurity measures challenge farmers because of numerous contamination routes. We plan to engage farmers and scientists to develop computer simulation models to design and investigate the efficacy of measures helping farmers mitigate this food safety threat.

    A paradoxical idea: Stimulating integration through spatially concentrating refugees at the microlevel?
    C.J. Huisman (Delft University of Technology)

    The need for better integration outcomes in the Netherlands is urgent. Social connections play a vital role in integration, while current policy is based on dispersing refugees at several geographical scales. This project provides insight into the effects of spatial clustering and spatial isolation on the networks of refugees.

    Sensorized shoes for gait monitoring and biofeedback rehabilitation in Parkinson’s patients
    Dr. A.G.P. Kottapalli (University of Groningen)

    Parkinson’s disease (PD) is a neurodegenerative disorder associated with deteriorated posture and gait. Herein, we propose low-cost sensorized shoes for patients to monitor gait and avoid fall conditions through a biofeedback voice alert. The technology can be used at home or rehabilitation centres for improved care and diagnosis of PD.

    Achieving a smoke-free generation by 2040 among disadvantaged youth
    Dr. M.A.G. Kuipers (Amsterdam UMC - Location AMC)

    At the current rate, the Smoke-free Generation goal for 2040 will not be achieved among disadvantaged youth. This study will map the complex adaptive system that drives smoking uptake in this group, and at which points interventions and policies will need to change the system to contribute to smoking prevention.

    Unfired brick made from mud and cow-dung that can regulate indoor climate
    Y. Kulshreshtha (Delft University of Technology)

    The energy required for building material production and space heating can be minimised by using mud bricks that have capability to regulate the indoor climate of buildings. The proposed brick is produced using cow-dung in a unique manner which improves the properties of climate regulation and water-resistance.

    ENVELOPE (ENhanced Vehicle Evaluation Leading to Optimized PErformance)
    K. Kural MSc (HAN University of Applied Sciences)

    Everything what is being physically transported generates a carbon footprint. It is an aim of ENVELOPE project to develop methodology enabling to safely deploy more energetically efficient vehicles for the road freight transport which reduce the footprint.

    T-cell repertoires as biomarker for vaccination efficacy
    J. Lanfermeijer (University Medical Center Utrecht)

    T‐cells play an important role in combatting pathogens. The unique and diverse T cell repertoire presents a personal signature that may be used to monitor vaccination response. We aim to investigate whether we can use T‐cell repertoire sequencing to identify vaccination induced memory immunity to allow for personalized vaccination strategies.

    Ultra-Fast Volumetric 3D Bioprinting to Drive Osteochondral Regeneration
    R. Levato (University Medical Center Utrecht)

    New 3D bioprinting technologies can enable the production of functional man-made human tissues, which can be used in regenerative medicine to restore the lost function of damaged knee joints. Herein, we will develop an innovative ultra-rapid volumetric bioprinting strategy to produce stem cell-laden bone and cartilage grafts to tackle osteoarthritis.

    Recommender requirements for pluriform perspectives in local public libraries
    Dr. C.C.S. Liem (Delft University of Technology)

    Public libraries may not be our primary knowledge source anymore, but still form a trusted environment for encountering contrasting perspectives. Analysing and visualizing loan behavior in local libraries across the country, we map what people can find today, and initiate discussions on how recommendation algorithms may extend this tomorrow.

    A resource allocation theory for the evolution of microbial communities
    Dr. J. Lischke (VU Amsterdam)

    Microbial communities are everywhere, both in natural and industrial settings. Our idea is to take optimal resource allocation theory, developed for single-species, and apply it to microbial communities. If applicable, it changes perspective from millions of possible species interactions to a handful of constraints acting on the ecosystem.

    Financial support needs of the people in debt
    T.E. Madern (Hogeschool Utrecht)

    Problematic debt has a high risk of escalating, making it crucial to intervene at an early stage. There is little knowledge on the kind of support people with financial problems need. With an interdisciplinary approach based on the fieldlab method, we seek to collect in-depth information about their support needs.

    GREENSED: GREen ENgineering solutions for SEDiments
    Dr. V. Magnanimo (University of Twente)

    Million m3 of sediments are dredged annually in Europe and disposed as waste, with enormous environmental impacts. GREENSED aims at developing cutting-edge treatments for sediments, using byproducts from local economy. Wastes will be converted into bysed-ment, an innovative building material, functional to support the sustainable development of our society.

    Personalizing health care in psychiatry by exploring biomarkers for staging models
    A. (Afra) van der Markt (Amsterdam UMC)

    Staging models have the potential to improve classification and treatment of patients with major psychiatric disorders. Useful models reflect underlying illness progress and are thus based on biomarkers. We aim to investigate if an aging marker derived from cerebral MRI shows stepwise progress concordant with stages of the staging model.

    3D printed biomimetic interfaces
    Dr. M.J. Mirzaali (Delft University of Technology)

    Attachment of extremely hard-soft materials is challenging. This project concerns unique approaches to finding optimum soft-hard interface designs inspired by natural soft-hard connections, e.g., cartilage-bone. Biomimetic interfaces will be engineered by introducing functional gradients at the interfaces using 3D bioprinting, opening up applications, e.g., osteochondral scaffold in tissue interface engineering.

    Catch Me If You Can: Mapping EU Company Mobility & Abuse-Detection
    Dr. K. Moodley (Maastricht University)

    Financial fraud and tax evasion by companies in the EU amount to losses of €110bn each year. This project aims to improve the detection of such crimes by automatically flagging potential abusers. It creates an innovative AI system that combines legal expertise, natural language processing, machine learning and knowledge graphs.

    Flying cow: Decreasing nitrogen and methane emissions from the dairy sector by using non-edible insect-derived products as feed ingredients
    Dr. ir. ing. D.G.A.B. Oonincx (Wageningen University & Research)

    Dairy cattle produce milk and meat, but also emit the greenhouse gas methane and excrete ammonia. By providing unfermentable, high quality, protein these emissions can be decreased. Currently, soybean meal is treated and used for this purpose. We will investigate if human inedible insect by-products can serve the same purpose.

    Understanding the dynamics of online sexual information sharing
    Dr. J.M.F. van Oosten (University of Amsterdam)

    Using machine learning, this project will investigate how (accurate and inaccurate) information and (positive and negative) attitudes on sexual behaviour are shared in online public spaces, such as comment sections of vlogs and Q&A forums. The findings will result in recommendations to optimize online and offline sexual education.

    Binging on processed foods; do processed foods trick our brain into overeating?
    A.M. van Opstal (Leiden University Medical Center)

    Obesity is a large burden on society caused by our current diet high in processed foods that elicits overeating. Understanding the regulatory processes in the brain as to why these foods are often overeaten will be imperative to pin-point how to reduce their negative effects and prevent or treat obesity.

    How does the living environment affect our lifestyles and associated greenhouse gas emissions? Working with citizens towards an answer
    F. Orsi (Wageningen University & Research)

    Our greenhouse gas footprint depends on lifestyles induced by our living environment’s spatial configuration. This project disentangles this connection by monitoring the lifestyles of a group of citizens via a custom developed app and involving them in the discussion of resulting data and the formulation of spatial planning recommendations.

    Safe and Tangible Interpretation of Machine Useful Limits for an Automated vehicle system via TEsting (STIMULATE) –Phase-1
    M. Padarthy (HAN University of Applied Sciences)

    The advantages of vehicle automation can be maximized by using automated vehicle systems within their operational limits. The proposed research aims at developing a feasible testing approach with which these limits can be robustly determined in correlation with real-world situations.

    EquiCity: Digital serious gaming for participatory city planning and management
    Dr. ir. A.R.G.G.M. Pereira Roders (Delft University of Technology)

    We propose a digital serious game for creating a ‘smart polder model’ to support decision making processes in urban planning and management. This game is to provide a participatory mechanism for balancing social, economic, and environmental sustainability goals in formulating and solving multi-criteria and multi-actor spatial decision- making problems.

    CItizens FInd microfibres iN Dutch watERs (CIFINDER)
    Dr. A. Praetorius (University of Amsterdam)

    Millions of microfibers can be released during a single wash load of synthetic textiles. This project will work with citizen scientists to assess how real-world habits - which clothes we wash, which settings we use - affect the release of microfibers, a major source for microplastics in the environment.

    Recycling of ammonia from animal manure
    Dr. ir. M. Ramdin (Delft University of Technology)

    The emission of nitrogen compounds such as ammonia (NH3) from agriculture forms a huge risk for the biodiversity in Natura 2000 areas. In this proposal, I will apply bio-based materials like natural deep eutectic solvents and biochar to capture and recycle ammonia at a manure processing company.

    Developing and testing a sponsorship pictogram to foster a safer and more transparent online media environment for Children
    Dr. E.A. van Reijmersdal (University of Amsterdam)

    Advertising in online videos is hard to recognize for children because it is often embedded. Together with children and the Netherlands Institute for the Classification of Audio-visual Media (NICAM), this project will develop and test a unique pictogram that signals whether a video contains advertising and that enhances online transparency.

    SPREAD: reduce Scabies impact on Poverty with a tool to estimate prevalence based on self-diagnosis.
    Y. Stienstra (University Medical Center Groningen)

    Scabies is linked to poverty. Mass-drug administration, treating everyone in the community at risk, is needed to reduce its burden. Policy makers have difficulties to decide on the size of the intervention needed. We will develop an interactive, digital tool to provide prevalence rates based on self-diagnosis by community members.

    Unravelling the mysteries of muscle injuries by delving into new dynamic measurements during high-speed running
    J.J.M. Suskens (Amsterdam UMC - Location AMC)

    Acute muscle injuries are the most prevalent sports injuries, and the number has not decreased over the last decade. Current management has a static, isolated approach, which is deficient. We aim for dynamic testing of the hamstring muscles during high-speed running in order to unravel the aetiology of muscle injuries.

    Invoking the Sacred: Towards Alternative Strategies Against Climate Conflicts
    Dr. J. Tarusarira (University of Groningen)

    Climate change is fuelling violent conflicts and undermining international peace and security. The role of sacred beliefs and practices in climate-induced conflicts remains understudied. This project interrogates how framing climate-induced conflicts in terms of sacred beliefs and practices influences the peace and reconciliation strategies adopted by policymakers and NGOs.

    Changes in neighbourhood walkability: an avenue to promote physical activity in old age?
    E.J. Timmermans MSc (Amsterdam UMC - Location VUmc)

    Although health benefits of physical activity are well-established, most older adults are insufficiently physical active. Social and physical neighbourhood characteristics, and their interactions, potentially affects their physical activity levels. Combining unique environmental data with individual-level cohort data, we will gain novel insights on environmental determinants of older adults’ physical activity.

    Virus-induced hearing loss: a study in inner ear cells
    A.C.T.M. Vossen (Leiden University Medical Center)

    Congenital infection with cytomegalovirus (CMV) is an important cause of hearing loss in children. An innovative laboratory model of the inner ear will be used to study how CMV leads to hearing loss and whether we can prevent or treat infection in order to reduce hearing loss.

    The role of evolution in the infant microbiome
    Dr. M.T. Wortel (University of Amsterdam)

    Our body consists of similar numbers of human and microbial cells, and while human cells cannot evolve within our life-time, fast-growing microorganisms do. Is their evolution important or are they replaced by strains from the environment? This study will reveal the prevalence of evolution in the infant gut microbiome.

    How Nature prevents protein aggregation in cells
    Prof. dr. S. Woutersen (University of Amsterdam)

    We will investigate how nature uses molecules such as ATP to prevent the aggregation of proteins in cells. This research is important for understanding the origins of life, but also for understanding and preventing diseases such as Alzheimer’s and Parkinson’s, which are caused by the aggregation of proteins.