Genetic and environmental risk factors for substance use


For my PhD project into genetic and environmental risk for substance use I would like to use large genome-wide datasets. In order to calculate polygenic risk scores and run genome-wide association analyses I will need large computational capacity. I would like to make use of the LISA system for at least three studies in the coming years, and have a very detailed plan for the first study. For this first plan I would like to calculate polygenic risk scores for 2500 individuals using LD regression.


Project number


Main applicant

J.A. van Rijswijk-Pasman MSc

Affiliated with

Radboud Universiteit Nijmegen, Faculteit der Sociale Wetenschappen, Behavioural Science Institute (BSI)


28/10/2017 to 15/11/2020