NWA-ORC awarded grants round 2018


Grants are given within the ranges of 0.5-2 million euros, 2-5 million euros and 5-10 million euros. The projects below receive funding for their research.

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Overview per budget range

Budget range 0.5 - 2 million euros

> ProMiSe: Tackling defective Prefrontal development in Mendelian Syndromes - a compelling (pre-)clinical integrative approach

Single gene disturbances can lead to severe developmental and behavioral problems. We suspect that deviant development of the pre-frontal cortex due to unique gene mutations is highly important. With our multidisciplinary approach we aim to provide a roadmap to integrate neurocognitive and biological knowledge to improve patient care.

Main applicant: Dr. S.M. Kolk (Radboud University Nijmegen)

Participating institutions: Leiden University, Leiden University Medical Center, University of Amsterdam, Radboud University Medical Center, University Medical Center Utrecht MIND facility, Scientific Volume Imaging (SVI), Sonidel Limited, Stemcell Technologies, Stevig/Vincent van Gogh, VG Netwerken (Zeldsamen), Center for Human Drug Reserach (CHDR) 

Amount rewarded: 1.6 miljoen euros

> Heritages of Hunger: Societal Reflections on Past European Famines in Education, Commemoration and Musealisation

European famines legacies continue to impact debates about economic decline, refugees and Brexit. They are re-evoked to stress transnational conflict, but actually offer potential to promote mutual understanding. This project investigates how educational practices (schools, heritage sites) can create awareness of famines as heritages of shared experiences and past solidarity.

Main applicant: Dr. M.C.M. Corporaal (Radboud University Nijmegen)

Participating institutions: NIOD Institute for War, Holocaust and Genocide Studies, Resistance Museum, EURO-CLIO, Museum Rotterdam, Netherlands Institute in Saint Petersburg, Red Star Line Museum, Irish Heritage Trust (National Famine Museum), Nerve Centre Derry, Universidad de Granada, Centro Documental de la Memoria Histórica, Holodomor Research and Education Centre Kyiv, Kuopio Cultural History Museum, Finnish Labour Museum, Holodomor Research and Education Centre Toronto, Ireland Park Foundation 

Amount rewarded: 1.6 million euros

> New, rational therapy decisions for developmental brain disorders: Integrating quantitative patient assessment, cellular assays and nanotechnology (NewTDec)

Autism spectrum disorder is heterogeneous in clinical presentation, causes and treatment responses. Personalized treatment requires physiological measures and rational treatments. The researchers use novel methods to quantify imbalances in brain activity in patients with autism, to study in patient-own neurons which drug candidates are likely to restore balanced brain activity, and perform clinical trials to validate treatment efficacy.

Main applicant: Dr. H. Bruining (UMCUtrecht)

Participating institutions: Radboud University Medical Center, VU Amsterdam, Amsterdam UMC, University of Twente, Multichannel Systems, SmarTip, NBT Analytics, Bronkhorst High-Tech

Amount rewarded: 1.8 million euros

> Optoacoustic sensor and ultrasonic microbubbles for dosimetry in proton therapy

Radiation therapy with X-ray is the standard for cancer treatment. In contrast, proton therapy treats only the tumour without damaging the surrounding tissue. By using microbubbles and a new very sensitive optical-ultrasound receiver, the exact position and dose of the proton-beam can be monitored essential for optimal treatment.

Main applicant: Prof. dr. ir. N. de Jong (Delft University of Technology)

Participating institutions: Erasmus University Medical Center, TNO The Hague, TNO Rijswijk, TNO Delft, HollandPTC, Bracco, Maastro Clinic, Maastricht University, Smart Photonics, ZonPTC

Amount rewarded: 1.7 million euros

> Preventing and Tackling the Opioid Epidemic

Opioids are useful painkillers, but they can cause serious adverse effects and addiction. In the Netherlands, the use of opioids is increasing rapidly. To prevent an US-like epidemic of problematic use, the consortium will investigate the causes and consequences of increased opioid use, and strategies to reduce the problematic use of opioids.

Main applicant: Prof. dr. M.L. Bouvy (Utrecht University)

Participating institutions: Leiden University Medical Center, SIR institute for pharmacy practice, Radboud University Medical Center, University Medical Center Utrecht, Canisius-Wilhelmina Hospital, Sint Maartens Clinic, KNMP (Dutch Royal Pharmacists’ Association), CBG (MEB, medicines evaluation board), National Healthcare Institute, Trimbos

Amount rewarded: 1.8 million euros

> Quantum microscopy: A new tool for future technologies

Quantum technology has the potential to transform global industries and markets. This revolution requires the ability to image how electrons behave in quantum systems. Collaborating with industry, we will develop a ‘quantum microscope’ that uses diamond sensors to image electrons with nanometer resolution, from near absolute-zero to above room temperature.

Main applicant: Dr. T. van der Sar (Delft University of Technology)

Participating institutions: TNO Delft, Leiden University, QuTech, Applied Nanolayers BV, Leiden Spin Imaging BV

Amount rewarded:1.3 million euros

> Self Defense:  Mimicking  natural  deterrent  strategies  in  plants  using adhesive  spheres  and  volatiles

Currently the protection of our crops is to a large extend based on the use of chemical insecticides, many of which will soon be banned by EU legislation. Inspired by nature, chemists and biologists team up to develop a revolutionary new way of plant protection by mimicking adhesive leaf hairs.

Main applicant: Prof. dr. P.G.L. Klinkhamer (Leiden University)

Participating institutions: University of Groningen, Wageningen University & Research, Aeres University of Applied Sciences , Van Iperen, Holland Biodiversity, Holland Green Machine

Amount rewarded: 1.4 million euros

> Severe Pre-eclampsia adverse Outcome Triage (SPOT) score for women with pre-eclampsia remote from term: SPOT implementation and impact assessment study (SPOT-impact)

Knowing which pregnant women are at highest risk for poor outcomes, allows providing the right care at the right time to the right person. We will investigate how health providers in Ghana can use risk prediction in a way that respects women, their cultural preferences and involves them in decisionmaking.

Main applicant: Prof. dr. D.E. Grobbee (Leiden University)

Participating institutions: KIT Royal Tropical Institute, University of Amsterdam, Utrecht University, University of Tennessee

Amount rewarded: 1.3 million euros

> TRansition Into Active Living: TRIAL

Our society reached a pinnacle in physically inactive behaviour that affects all age groups. In this interdisciplinary project we target one’s social network to promote persistent changes in active behaviour during major life transitions. We will develop tools that help professionals to stimulate persons to become and remain physically active.

Main applicant: Prof. dr. B. Steenbergen (Radboud University Nijmegen)

Participating institutions: Mulier Institute, HAN University of Applied Sciences, KNHB, GGD Gelderland-South, Municipality of Nijmegen, NL-Actief, KNVB, Adaptics, Kennispraktijk, National Platform on Sustainable Employability, Europactive, Start2Move, THP2Europe B.V., KNLTB

Amount rewarded: 1.7 million euros

> Understanding and preventing moral injury among military and police personnel: Interdisciplinary research and intervention

A substantial number of military and police personnel develop ‘moral injury’: guilt, shame and anger resulting from perpetrating or experiencing moral transgression. Yet, both comprehensive knowledge and interventions regarding this condition are currently lacking. This project examines organizational, socio-technical and ethical-political factors in moral injury, and develops three preventive interventions.

Main applicant: Dr. W.M. Verkoren (Radboud University Nijmegen)

Participating institutions: Netherlands Defence Academy, Netherlands Veterans Institute, Police Academy, Arq Psychotrauma Expert Group

Amount rewarded: 1.2 million euros

 

Budget range 2 - 5 million euros

> CORTEX: the Center for Optimal, Real-Time Machine Studies of the Explosive Universe

Machine learning is everywhere: ask the virtual assistant in your phone. Big self-learning computers also help us understand the universe. Now we want to make these machines faster and keep up. Then we can figure out how massive cosmic explosions work. And help others that need fast self-learning machines.

Main applicant: Dr. A.G.J. van Leeuwen (ASTRON - Netherlands Institute for Radio Astronomy)

Participating institutions: Nikhef, SURFSara, Netherlands eScience Center (NLeSC), University of Amsterdam, Radboud University Nijmegen, Centrum Wiskunde & Informatica (CWI, the national research institute for mathematics and computer science), IBM Nederland B.V., BrainCreators B.V., ABN AMRO N.V., NVIDIA, NOVA, ILT

Amount rewarded: 4.5 million euros

> Insects as sustainable feed for a circular economy: interdisciplinary approach to value chain development

To develop insects as sustainable feed for a circular economy, we will investigate (1) insect production, focussing on insect health, insect welfare and intrinsic value of insects, (2) health and welfare of livestock fed with insects and (3) conduct an economic analysis of the new insect sector.

Main applicant: Prof. dr. M. Dicke (Wageningen University & Research)

Participating institutions: HAS University of Applied Sciences, University of Groningen, Protix, Buhler Insect Technology Solutions (BITS), Amusca Europe, Ministry of Agriculture, Nature and Food Quality, Dutch Society for the Protection of Animals, Rabobank Netherlands, Netherlands food and consumer product safety authority (NVWA), GD Animal Health, Southern Agriculture and Horticulture Organization (ZLTO)

Amount rewarded: 3.4 million euros

> Living on Soft Soils: Subsidence and Society

Ongoing subsidence is a complex problem for cities and polders in the Dutch lowlands. Old strategies for coping have limits. Based on deep investments in measuring and understanding subsidence, new strategies will be arranged, so that decisions on subsidence measures and strategies are based on figures in mm/yr and €/yr.

Main applicants: Dr. E. Stouthamer (Utrecht University)

Participating institutions: Wageningen University & Research, Delft University of Technology, Deltares, WEnR, TNO-GSN, Ministry of Infrastructure and Water Management, Rijkswaterstaat, Ministry of the Interior and Kingdom Relations, STOWA, HDSR (Water Authority Hoogheemraadschap De Stichtse Rijnlanden), WDOD (Water Board WDODelta), Province of Utrecht, Soft Soil Municipalities, Municipality of Gouda, SWECO, Tauw BV, NAM

Amount rewarded: 4.4 million euros

> PrimaVera: Predictive maintenance for Very effective asset management

PrimaVera realizes the full potential of predictive maintenance by developing (1) better measurements, fully utilising the potential of smart sensor technology (2) better predictions, through novel, accurate algorithms (3) better planning, by deriving user-centric optimal maintenance decisions, accounting for organizational factors. We orchestrate these steps in a holistic automated workflow.

Main applicant: Prof. dr. M.I.A. Stoelinga (University of Twente)

Participating institutions: Eindhoven University of Technology, The Hague University of Applied Sciences (HHS), Netherlands Aerospace Center (NLR), Radboud University Nijmegen, Saxion University of Applied Sciences, Rijkswaterstaat, Damen, Technobis, Alfa Laval, Royal NL Navy, NS, ASML, Royal IHC, Rolsch Asset Management, Water Board de Dollem, ORTEC Consulting Group

Amount rewarded: 4.4 million euros

> SYMPHONY: Orchestrating personalised treatment in patients with bleeding disorders

In SYMPHONY patients, doctors and scientists work together to personalise treatment in bleeding disorders by a patient-orchestrated approach. Harmonisation of efforts to improve laboratory tests, treatment, and our understanding of blood clot formation, will show us how to establish which treatment is best for each individual patient.

Main applicant: Dr. M.H. Cnossen (Erasmus University Medical Center)

Participating institutions: Sanquin Research, Amsterdam UMC, University Medical Center of Groningen, University Medical Center Utrecht, Netherlands Hemophilia Patient Society (NHVP), Dutch Association of HIV-treating physicians (NVHB), Dutch Society on Thrombosis and Haemostasis (NVTH), Bayer B.V., CSL Behring B.V., Sobi Benelux

Amount rewarded: 4.1 million euros

 

Budget range 5 - 10 million euros

> An Internet of Secure Things - INTERSECT

The Internet of Things represents one of the biggest challenges (and - as of today - failures) for cybersecurity and cyber-privacy. INTERSECT addresses this societal and technical challenge by adopting a completely new, foundational perspective that brings together security research (e.g. design, defence, attack generation) with legal and criminology approaches.

Main applicant: Prof. dr. S. Etalle (Eindhoven University of Technology)

Participating institutions: VU Amsterdam, Radboud University Nijmegen, Delft University of Technology, University of Twente, Tilburg University, Netherlands Institute for the Study of Crime and Law Enforcement, Fontys University of Applied Sciences, TNO, Amsterdam University of Applied Sciences, BDO Advisory B.V., Brainport Development N.V., Bosch Security Systems B.V., Centric Netherlands B.V., Compumatica secure networks B.V., Consumentenbond (Dutch Consumer Association), Fourtress BV, ICT Automatisering B.V., Ministry of the Interior and Kingdom Relations, Océ-Technologies B.V., Omron Europe B.V., Oracle Nederland B.V., Royal Philips N.V., Qbit Cyber Security, Secura B.V., Foundation for Internet Domain Registration in the Netherlands (SIDN), Siemens Netherlands N.V., Signify Netherlands B.V., Simac Techniek N.V., SURFnet B.V., Synopsys Netherlands B.V., Technolution B.V., Verum Software Tools B.V.

Amount rewarded: 8.2 million euros

> Preparing for vector-borne virus outbreaks in a changing world: a One Health Approach

The Netherlands, with its dense population of humans and livestock, international transport and travel hubs, and water-dominated landscape is particularly vulnerable to infectious disease outbreaks. We aim to understand if and how changes in climate, farming, water management and travel lead to mosquito-borne disease outbreaks, in order to be better prepared.

Main applicant: Prof. dr. M.P.G. Koopmans (Erasmus University Medical Center)

Participating institutions: Utrecht University, University Medical Center Utrecht, Wageningen University & Research, Leiden University, Leiden University Medical Center, Radboud University Medical Center Nijmegen, Netherlands Institute of Ecology, Avans University of Applied Sciences, Deltares, Royal Netherlands Meteorological Institute (KNMI), National Institute for Public Health and the Environment (RIVM), Red Cross Blood Bank Curaçao, Sanquin, Technasium, Netherlands Centre for Monitoring of Vectors (CMV)

Amount rewarded: 9 million euros