NACTAR: (pre)clinical studies

This call for proposals is open for researchers who want to develop project proposals which aim for (pre-) clinical validation of new antimicrobial molecules and alternatives to antibiotics, which should become available for the healthcare system for a fair and affordable price.

Purpose

This NACTAR call for (pre)clinical studies is funded by Ministry of VWS, and the objective is to support studies that aim to bring newly developed antibiotic compounds, products and/or alternative treatments to the stage of (pre)clinical testing. It is expected that projects contribute to translation of previously developed compounds, therapies and/or treatments to the clinic, aimed at curing human infectious diseases caused by MDR bacteria.

To this end, activities may consist of (parts of) pre-clinical, phase 0, phase 1 or early stage phase 2 clinical study with clearly described (clinical) end-points. The intended approach must adhere to criteria from the European Medicines Authority (EMA) and/or the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH).

Who can apply

Scientists employed by (Technical) Universities situated in the Kingdom of the Netherlands, as well as institutes eligible for funding by NWO, can submit a proposal. In each proposal, one (1) company (SME, industry) can participiate in the project as (potential) user that is not obliged to contribute co-funding. 
Within the NACTAR call for (pre-)clinical studies, applicants may associate their name to one (1) proposal as main applicant and to one (1) proposal as co-applicant.

What to apply for

The funding that can be requested per project is minimum 200k€   up to maximum 1M euro for a project with maximum duration is 2 years. Project specific costs for tempory personnel, consumables and other materials can be financed from the project budget. 
Please read the guideline for applicants in the call for proposas carefully. The projects must start within 6 months after award of the project.

When to apply

  • The deadline for submitting pre-proposals is 14th of January 2020, at 14:00 uur CE(S)T.
  • The deadline for submitting full proposals is 24th of march 2020, at 14:00 uur CE(S)T.

Assessment

Criteria

Proposals will be assessed on the basis of the following three criteria.

  1. Project approach & team
  2. Relevance and innovative aspects
  3. Clinical and commercial potential

For each of these criteria evaluation aspects have been defined. 

Procedure

All submitted pre-proposals will be evaluated by the assessment committee based on assessment criterion 2. The advise of the assessment committee will be communicated to the applicants together with the comments from NWO regarding eligibility for preparation of the full proposal. Please be aware that pre-selection based on criterion 2 in relation to requested budget is optional in this phase. Pre-selection is enforced when four times more pre-proposals are submitted than can be funded from the available budget.  

Eligible full proposals will be submitted to expert assessment committee for evaluation and the applicants will be invited for an interview. The NWO Executive Board decides on whether or not to award funding to each research proposal based on the granting/ranking advice from the selection committee.

More information

The call for proposals for (pre-)clinical studies is part of the research programma NACTAR funded by the Ministery of Health Welfare and Sports and NWO. This call for proposals is executed by NWO Domain AES in close collaboration with The Netherlands Antibiotic Development Platform. 

No rights can be obtained from information on this webpage. For any questions related to this call or the provided documents please contact NWO Domain AES.

Details

Status

Open for preliminary proposals

Deadline

14 January 2020 14:00

Grant type

Programmatic

Budget

1 million euro

Science area

Applied and Engineering Sciences

Objective

Research (2019-2022)

Partners

Netherlands Antibiotics Development Platform - Ministry of Health, Welfare and Sport

Contact

Dr Gerdine Stout (Programme officer) Dr Gerdine Stout (Programme officer) +31 (0)30 6001325 g.stout@nwo.nl

Contact

Ms. dr. T. (Titia) Plantinga (Senior programme officer) Ms. dr. T. (Titia) Plantinga (Senior programme officer) +31 (0)30 6001307 t.plantinga@nwo.nl