Detailed project information

Visual information is crucial for goal-directed movements. For example, object size and orientation are important for grasping. The brain therefore has to emphasize relevant and suppress irrelevant information.

How perceptual features guide our actions is well known. However, the idea that intention, planning and execution of movements can change certain aspects of perception is new and not understood.

The proposed research investigates if motor systems use neural feedback connections to visual areas to influence perception, for eye movements and grasping. Functional imaging will visualize cortical processing during actions. Transcranial magnetic stimulation on feedback nodes can establish whether perception around movements is disrupted.

Articles

• AT Sack, DEJ Linden, M Lindner (2007). Object- and direction-specific interference between manual and mental rotation.. Perception & Psychophysics. pp. 1435-1449
• HI van Mier, A Kaas, AT Sack, J Lataster, M Fingal (2007). The effect of visuo-haptic congruency on haptic spatial matching. Experimental Brain Research. pp. 75-85
• DEJ Linden, R Goebel, A Kohler, J Baudewig, AT Sack, P Dechent, S Bestmann (2007). Imaging the brain activity changes underlying impaired visuospatial judgments: Simultaneous fMRI, TMS, and behavioral studies.. Cerebral Cortex . pp. 2841-2852
• A Henik, A Kaas, R Cohen-Kadosh, AT Sack, K Cohen-Kadosh, T Schuhmann, R Goebel (2007). Virtual dyscalculia induced by parietal lobe TMS impairs automatic magnitude processing. Current Biology. pp. 689-693
• AT Sack, R Goebel, E Formisano, C Jacobs (2008). Dynamic Premotor-To-Parietal Interactions during Spatial Imagery. Journal of Neuroscience. pp. 8417-8429
• W. Huijbers, S.F.W. Neggers, J.L. Kenemans, H.M. van Ettinger-Veenstra, M. Vink, T.P. Gutteling (2009). fMRI guided TMS on cortical eye fields: the frontal but not intraparietal eye fields regulate the coupling between visuo-spatial attention and eye movements.. Journal of Neurophysiology. pp. 3469-3480
• T Schuhmann, NO Schiller, R Goebel, AT Sack (2009). MRI-guided TMS neuronavigation reveals temporal characteristics of functional activation in Broca?s area during active picture naming. Cortex. pp. 1111-1116
• AT Sack, J Schwarzbach, S van der Mark, T Schuhmann, R Goebel (2009). Symbolic action priming relies on intact neural transmission along the retino-geniculo-striate pathway. NeuroImage. pp. 284-293
• R Goebel, R Cohen-Kadosh, V Walsh, T Schuhmann, AT Sack, M Moerel (2009). Optimizing functional accuracy of TMS in cognitive studies: a comparison of methods. Journal of Cognitive Neuroscience. pp. 207-221
• T.P. Gutteling, J.L. Kenemans, S.F.W. Neggers, H.M. van Ettinger-Veenstra (2010). Lateralized frontal eye field activity precedes occipital activity shortly before saccades: evidence for cortico-cortical feedback as a mechanism underlying covert attention shifts. Journal of Cognitive Neuroscience. pp. 1931-43-1943